At Sahkar Pharmaceuticals Pvt. Ltd., we manufacture and supply 2-Methoxy-5-Nitrophenol, also widely known as 5-Nitroguaiacol, a versatile aromatic organic intermediate used in agrochemical, pharmaceutical, specialty chemical and organic-synthesis applications.
For us, manufacturing a specialty chemical is not simply about producing a chemical compound. It is about delivering consistent quality, reliable specifications and a dependable supply to industries that use the material as a building block for their own products and processes.
Our manufacturing operations are based in Ahmedabad, Gujarat, India, and we have been engaged in the manufacture and supply of chemical and pharmaceutical intermediates since 2005.
What is 2-Methoxy-5-Nitrophenol?
2-Methoxy-5-Nitrophenol is an aromatic organic compound with the following key identifiers:
Chemical Name: 2-Methoxy-5-Nitrophenol
Common Synonym: 5-Nitroguaiacol
CAS Number: 636-93-1
Molecular Formula: C₇H₇NO₄
Molecular Weight: 169.13 g/mol
Physical Form: Crystalline powder
Appearance: Brownish to yellow / yellow to light-brown powder
Application: Organic and agrochemical intermediate
The molecular formula, molecular weight and CAS identification are also independently listed by PubChem and TCI for 5-Nitroguaiacol.
Our published product specification describes the material as a brownish-to-yellow powder, with technical-grade assay specifications available for industrial requirements.
Why 2-Methoxy-5-Nitrophenol Matters to Industry
The importance of 2-Methoxy-5-Nitrophenol comes from its role as a functional aromatic building block.
The molecule contains methoxy, hydroxyl and nitro functional groups. These chemical functionalities make it useful as a starting material or intermediate in downstream chemical synthesis.
At Sahkar, we therefore view 2-Methoxy-5-Nitrophenol not simply as an individual product, but as a building block that supports several downstream industries.
1. Agrochemical Industry
One of the major application areas associated with 2-Methoxy-5-Nitrophenol is the agrochemical industry.
The compound is used in the production of 5-nitroguaiacol derivatives, including its sodium salt, Sodium 5-Nitroguaiacolate. The sodium derivative is used in agricultural plant-growth-regulator and biostimulant formulations. Sahkar also manufactures Sodium 5-Nitroguaiacolate as a separate product.
This creates an important connection between our intermediate manufacturing capabilities and the agricultural-input industry.
Downstream applications can include products associated with:
• Plant growth regulators
• Agricultural biostimulants
• Crop-growth formulations
• Agrochemical intermediates
• Specialty crop-input formulations
Important distinction: 2-Methoxy-5-Nitrophenol and Sodium 5-Nitroguaiacolate are different chemical substances. The latter is the sodium salt derived from the former and has its own CAS number and specifications.
2. Pharmaceutical Industry
The second important area is pharmaceutical and medicinal chemistry.
2-Methoxy-5-Nitrophenol is used as an organic synthesis intermediate in routes toward more complex molecules. Published chemical references describe its use in synthesis involving VEGF and tyrosine-kinase inhibitor compounds, as well as GABA analogues and phosphodiesterase inhibitors such as rolipram.
For pharmaceutical manufacturers and research organizations, the value of such an intermediate lies in its ability to participate in multi-step chemical synthesis.
Therefore, the product can be relevant to:
• Pharmaceutical intermediate manufacturing
• Medicinal chemistry
• API development research
• Organic synthesis
• Fine-chemical development
• R& D laboratories
We emphasize that 2-Methoxy-5-Nitrophenol itself should be understood as a chemical intermediate/building block and not as a pharmaceutical API.
3. Specialty Chemical Industry
Specialty chemicals require intermediates with defined chemical characteristics and reproducible specifications.
Because of its substituted aromatic structure, 2-Methoxy-5-Nitrophenol can serve as a building block for downstream specialty chemical synthesis.
Its potential relevance extends to manufacturers developing:
• Fine chemicals
• Specialty intermediates
• Custom synthesis products
• Research chemicals
• Functional aromatic compounds
For such applications, factors such as purity, impurity profile, physical characteristics and batch consistency can be important purchasing considerations.
4. Organic Synthesis & Chemical R& D
Beyond large-scale industrial applications, 2-Methoxy-5-Nitrophenol is also relevant to organic synthesis and chemical research.
Its defined molecular structure allows chemists to use it as a starting material for further chemical transformations.
This makes the material relevant to:
Chemical manufacturers → Intermediate → Further synthesis → Specialty / pharmaceutical / agrochemical product
This role as a chemical building block is one of the reasons 2-Methoxy-5-Nitrophenol continues to have relevance across multiple chemical value chains.
5. Research & Development
Research laboratories and chemical R& D organizations may require 5-Nitroguaiacol for:
• Synthetic chemistry
• Route development
• Intermediate screening
• Process development
• Analytical research
• Development of specialty molecules
International chemical suppliers such as TCI also identify 5-Nitroguaiacol as 2-Methoxy-5-Nitrophenol and list it as a chemical research product.
Our Approach to Manufacturing
At Sahkar Pharmaceuticals, our objective is to provide industrial customers with a reliable source of specialty chemical intermediates.
We focus on:
Consistent Quality
We manufacture against defined product specifications and quality requirements.
Reliable Supply
Our manufacturing capabilities are designed to support industrial and commercial requirements.
Technical Specifications
Important parameters such as assay, appearance, melting point and loss on drying can be evaluated against the applicable specification and batch documentation. Our published specification, for example, identifies a melting-point range of approximately 103–107°C and provides assay and impurity parameters.
Industrial Packaging
Packaging can be aligned with the customer's commercial and handling requirements.
Customer-Oriented Manufacturing
We work with customers requiring chemical intermediates for manufacturing, formulation and downstream synthesis.
